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HIV-infected children vaccination coverage and safety in a Western European cohort: a retrospective study.

Identifieur interne : 000571 ( Main/Exploration ); précédent : 000570; suivant : 000572

HIV-infected children vaccination coverage and safety in a Western European cohort: a retrospective study.

Auteurs : María Fernández-Ibieta [Espagne] ; José T. Ramos-Amador ; Ismael Au N-Martín

Source :

RBID : pubmed:17524201

Descripteurs français

English descriptors

Abstract

Since the implementation of highly active antiretroviral therapy in HIV-infected children, response to scheduled vaccines may determinate future morbidity and mortality. The aims of this study have been to describe the current vaccine coverage, vaccine safety and concordance with vaccine recommendations of the 68 HIV-infected children and adolescents followed up in our Unit. Forty-four percent of the children received at least one dose of the oral polio vaccine (OPV). Only 9.1% needed and received a second set of hepatitis B virus immunization because of low vaccine response. Only 14.7% were vaccinated against varicella. Coverages of 82.3% and 100% have been reached with the 23-valent and the 7-valent pneumococcal vaccines, respectively. Meningococcal conjugated vaccine uptake was moderate (80.8%). Influenza annual vaccination coverage was poor: only 22.7% had well-documented yearly vaccines. In our experience, vaccine coverage is lower in those vaccines administered in primary care centres compared with the immunizations given at the hospital. OPV administration did not cause any adverse effect in the children or in their families. Vaccine coverage in HIV-infected children was suboptimal.

DOI: 10.1258/095646207780749763
PubMed: 17524201


Affiliations:


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Le document en format XML

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